Preventing Cancer Before It Starts: Jonathan Cohen’s Bold Vision for Early Detection and Investor Impact
How 20/20 Biolabs Is Democratizing Cancer Screening with Affordable, At-Home Blood Tests—And Offering Investors A Rare Chance at Near-Term Liquidity
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Despite staggering investments in cancer treatments, most patients still face limited benefits—especially when diagnosed late. Jonathan Cohen, founder and CEO of 20/20 Biolabs, believes that the true key to saving lives lies not in better treatments, but in earlier detection.
“I saw massive funding of and spending by biotech companies in developing treatments, but very little going to companies focused on early disease detection and prevention, which can be far more impactful,” Cohen says. “Unlike with infectious disease, the effectiveness of treatments for cancer and most chronic diseases is quite limited. Even the latest approved cancer drugs typically extend the lives of those with metastatic disease by only a few weeks or 2-3 months at best.”
By contrast, prevention—particularly early detection—offers a much better return on investment, not only in dollars but in lives saved. Through 20/20 Biolabs, Cohen has launched a line of AI-powered blood tests designed to do just that.
A More Equitable, Accessible Solution
Under the OneTest brand, Cohen’s team has developed two main products: OneTest for Cancer, a multi-cancer early detection (MCED) blood test, and OneTest for Longevity, which measures inflammatory biomarkers. The second product is expected to launch in October.
“Our multi-cancer early detection blood test helps detect cancers at earlier stages when they can most effectively be treated,” Cohen explains. “Over 20,000 tests have been purchased to date, and many have already benefitted from our test.”
What makes OneTest stand out is its accessibility. “We offer the only multi-cancer early detection blood test in the U.S. market that is available for under $250, can be collected at home, and which has good sensitivity for earlier stage cancers,” he says.
That’s a stark contrast to competitors. “Our main competitor—the Galleri test from Grail—costs just under $1,000, requires a phlebotomy blood draw, and misses most early-stage cancers according to Grail’s own published data.”
The company has found a key audience in a high-risk population: firefighters. “Firefighters—who have proven high incidence and deaths from various cancers—have been a major part of our customer base, with over 250 fire departments using our MCED.”
From Crowdfunding to Nasdaq
While the science is compelling, Cohen is equally focused on scaling the business. “We are taking concrete steps to become a Nasdaq listed company before the end of this year,” he says. “That includes filing a draft Registration Statement, engaging an investment banking firm with significant experience in direct listings, and submitting a listing application with Nasdaq.”
The vision doesn’t stop with an IPO. “This status, coupled with some large investments, will enable us to not only scale our current product line but to ‘roll-up’ several related companies through M&A,” Cohen explains. “These include companies that are vertically integrated with us—suppliers and marketing channels—as well as companies with complementary products we can offer our consumers.”
That strategy offers both vertical and horizontal growth, aimed at building a healthtech powerhouse with wide-ranging capabilities.
A Refreshing Business Discipline
Unlike many biotech startups that focus heavily on research and proprietary science, 20/20 Biolabs has taken a more pragmatic route—one grounded in solving real problems with proven tools.
“Focus on solving a big problem rather than a technical solution,” Cohen advises other founders. “This is a very common mistake with biotech start-ups in particular. Companies with scientific founders too often fall in love with their technology and can be blinded to alternative approaches that might perform equally well with far less developmental costs and timelines.”
To that end, 20/20 Biolabs’ cancer detection tests measure widely accepted biomarkers such as CEA and CA 19.9—well-known in the medical community. What sets the company apart is not inventing new biomarkers, but applying machine learning to interpret results more powerfully, and distributing the test in a convenient, affordable format.
“Development of our multi-cancer test… leveraged real-world data from parts of the world where such testing is commonplace,” Cohen says. “Thus, we invested far less than 1% of the billions of dollars funds spent by Grail, and many of our consumers and industry experts believe we have a superior test.”
An Unusual Investment Opportunity
In the crowded world of regulated investment crowdfunding, few offerings stand out like 20/20 Biolabs’. For investors, the company is offering a rare feature: a convertible debt round with a built-in liquidity path.
“We are offering a convertible debt round that automatically converts to equity upon listing on Nasdaq at a 20% discount,” Cohen explains. “If we fail to go public within 24 months, the investor gets their money back with 15% interest.”
That’s a striking offer, particularly in a crowdfunding environment where investors often wait years—and sometimes forever—for an exit.
“Such an opportunity for near-term profits is likely unprecedented among crowdfunding companies, 98% of which have failed to give their shareholders a path to liquidity despite more than 10 years since equity crowdfunding went online,” he says.
For impact investors seeking both financial return and social benefit, the offering provides an enticing mix: a real shot at liquidity combined with the chance to support life-saving innovation.
The Entrepreneur Behind the Mission
Jonathan Cohen brings a unique mix of legal, scientific, and business experience to the venture. A registered patent attorney with over 25 years in biotech intellectual property, Cohen previously served as general counsel for two publicly traded companies—Ventana Medical Systems (acquired by Roche) and Oncor Inc. He also holds a Master of Science in Biotechnology from Johns Hopkins and a law degree from American University.
As CEO of 20/20 Biolabs, Cohen co-invented both OneTest and another product, BioCheck, and has led deals with companies like Johnson & Johnson, IBM, and Abbott Diagnostics.
He’s not just an innovator—he’s an advocate. Cohen has been active in lobbying for small biotech and diagnostics companies at both the state and federal levels, championing policies to support emerging science-based ventures.
A Test—and an Investment—for the Future
With its upcoming launch of a longevity test, plans for a Nasdaq listing, and a compelling investment structure, 20/20 Biolabs stands at a pivotal moment.
For Cohen, the mission remains simple: save more lives, earlier, and for less money.
That’s the kind of vision that speaks not only to patients and families—but also to a new generation of impact-minded investors ready to change the world, one smart bet at a time.
Jonathan Cohen’s Bio
Mr. Cohen is the founder of 20/20 Biolabs and has served as Chief Executive Officer, President, and a director since its inception. He is a co-inventor of two of our most successful products, OneTest and BioCheck, and has led the commercial launch and sales of both. He has also spearheaded license, research, technology transfer, investment, and sales and marketing agreements with Fortune 500 companies such as Eastman Kodak, Abbott Diagnostics, Johnson & Johnson, IBM, and Ping An, the largest health insurance company in China. Mr. Cohen has also been a leading advocate in Annapolis, MD and on Capitol Hill on behalf of small and emerging biotechnology and diagnostics companies. Before founding our company, Mr. Cohen was patent and general counsel for two publicly traded companies, Ventana Medical Systems Inc. (acquired by Roche diagnostics in 2008), from 1999 to 2000, and Oncor Inc., from 1997 to 1999. Mr. Cohen is a registered patent attorney with more than 25 years of experience in biotechnology patents and licensing matters. Mr. Cohen has a Master of Science Degree in Biotechnology from Johns Hopkins University and a law degree from the American University. We believe that Mr. Cohen is qualified to serve on our board of directors due to his experience in our industry and knowledge of our company.
Campaign Details:
20/20 Biolabs is raising funds via PicMii. The campaign closes August 8. To learn more, visit: picmiicrowdfunding.com.
Max-Impact Members
The following Max-Impact Members provide valuable financial support:
Carol Fineagan, Independent Consultant | Hiten Sonpal, RISE Robotics | Lory Moore, Lory Moore Law | Marcia Brinton, High Desert Gear | Mark Grimes, Networked Enterprise Development | Matthew Mead, Hempitecture | Michael Pratt, Qnetic | Dr. Nicole Paulk, Siren Biotechnology | Paul Lovejoy, Stakeholder Enterprise | Pearl Wright, Global Changemaker | Ralf Mandt, Next Pitch | Scott Thorpe, Philanthropist | Sharon Samjitsingh, Health Care Originals | Add Your Name Here
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